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Differences in Metabolism (species, gender, age, diseases)

P74
In Vitro Identification of CYP450 and FMO Mediated Metabolic Pathways to Support Drug Discovery
Yiding Hu, Genzyme Corp; Sirimas Sudsakorn, Genzyme Corp; Nanqun Zhu, Genzyme Corp; Hanlan Liu, Genzyme Corp; Thomas O'Shea, Genzyme Corp
P75
Characterization of the Impact of Life Stage on Xenobiotic Metabolizing Enzyme Expression and Gene - Chemical Interactions in the Liver
Janice S. Lee, EPA; William O. Ward, EPA; Hongzu Ren, EPA; Beena Vallanat, EPA; Michael J. DeVito, NIEHS/NTP; Jon C. Corton, EPA
P76
Gene Expression of Hepatic Metabolizing Enzymes and Transporters in a Traumatic Brain Injury (TBI) Rodent Model
Gail D. Anderson, University of Washington; Fred M. Farin, Univeristy of Washington; Theo Bammler, University of Washington; Richard Beyer, University of Washington; Michael R. Hoane, Southern Illinois University
P77
Species Differences in Metabolic Clearance due to UDP-Glucuronosyltransferase Substrate Selectivity: Impact During Early Drug Discovery
Mark Niosi, Pfizer; Theunis C. Goosen, Pfizer Inc.; Brendon Kapinos, Pfizer; Matthew D. Troutman, Pfizer Inc.; Kentaro Futatsugi, Pfizer; Alfin D. N. Vaz, Pfizer Global R & D
P78
Sulfotransferase expression and activity is altered by human metabolic disease
Emine Bihter Yalçin, University of Rhode Island; Karissa Neira, University of Rhode Island; Renae Gupta, University of Rhode Island; Angela L. Slitt, University of Rhode Island; Roberta S. King, University of Rhode Island
P79
The Effect Of Sterculic Oil Intervention On Drug Metabolism Enzyme Activity And Transporter Expression In LETO/OLETF Model Of Obesity
Manoj S. Chiney, University of Minnesota; Harrison Tam, University of Minnesota; Laura C. Ortinau, University of Missouri; James W. Perfield II, University of Missouri; L'Aurelle Anna Lee Johnson, University of Minnesota
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