19 Symposium 9: Translational and Post-translational Regulation of Drug Metabolizing Enzymes

Cytochrome P450 degradation: Biological findings, clinical implications and misconceptions set to rest as we keep gp78/CHIPping away
Maria Almira Correia, UCSF; Sung-Mi Kim, UCSF; YongQiang Wang, UCSF; Poulomi Acharya, UCSF; Yi Liu, UCSF
The conformation of the P450-oxygenase domain of NO-synthase controls the Hsp70- and Hsp90-mediated ubiquitination of the enzyme
Yoichi Osawa, University of Michigan Medical School; Hwei-Ming Peng, University of Michigan Medical School; Kelly M. Clapp, University of Michigan Medical School; Miranda Lau, University of Michigan Medical School; Robert L. Barry, University of Michigan Medical School; Yoshihiro Morishima, University of Michigan Medical School
Reactive nitrogen species (RNS) in the regulation of cytochrome P450 proteolysis: NO hiding place for RNS-modified P450s
Edward T. Morgan, Emory University School of Medicine; Haiyan Sun, Shenzhen Polytechnic; Kyung-bo Kim, University of Kentucky College of Pharmacy; Choon-myung Lee, Emory University School of Medicine
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